2024

• El Omari, K., Forsyth, I., Duman, R., Orr, C. M., Mykhaylyk, V., Mancini, E. J., & Wagner, A. (2024). Utilizing anomalous signals for element identification in macromolecular crystallography. Acta Crystallographica Section D: Structural Biology, 80(Pt 10), 713-721. doi:10.1107/S2059798324008659
  Article. View online.
• Norris, R., Jones, J., Mancini, E., Chevassut, T., Simoes, F., Pepper, C., . . . Mitchell, S. (2024). Patient-specific computational models predict prognosis in B cell lymphoma by quantifying pro-proliferative and anti-apoptotic signatures from genetic sequencing data. Blood Cancer Journal, 14(1), pages. doi:10.1038/s41408-024-01090-y
  Article. View on figshare.

2023

• El Omari, K., Duman, R., Mykhaylyk, V., Orr, C. M., Latimer-Smith, M., Winter, G., . . . Wagner, A. (2023). Experimental phasing opportunities for macromolecular crystallography at very long wavelengths. Communications Chemistry, 6(1). doi:10.1038/s42004-023-01014-0
  Article. View online.
• Agnarelli, A., Betran, A. L., Papakyriakou, A., Vella, V., Samuels, M., Papanastasopoulos, P., . . . Giamas, G. (2023). The inhibitory properties of a novel, selective LMTK3 kinase inhibitor. International Journal of Molecular Sciences, 24(1), e865 1-15. doi:10.3390/ijms24010865
  Article. View on figshare.
• Norris, R., Jones, J., Mancini, E., Chevassut, T., Pepper, C., Pepper, A., & Mitchell, S. (2023). Patient-specific computational models predict prognosis in B cell lymphoma by quantifying pro-proliferative and anti-apoptotic signatures from genetic sequencing data. doi:10.1101/2023.07.10.548371
  Preprint. View online.

2022

• Agnarelli, A., Mitchell, S., Caalim, G., Wood, D., Harris, L., Chevassut, T., . . . Mancini, E. (2022). Dissecting the impact of bromodomain inhibitors on the IRF4-MYC oncogenic axis in multiple myeloma. Hematological Oncology, 40(3), 417-429. doi:10.1002/hon.3016
  Article. View on figshare.
• Wagstaff, M., Tsaponina, O., Caalim, G., Greenfield, H., Harris, L., Mancini, E., . . . Morgan, R. (n.d.). Crosstalk between ß-catenin and WT1 signalling activity in acute myeloid leukemia. Haematologica, pages. doi:10.3324/haematol.2021.280294
  Article. View on figshare.

2021

• Agnarelli, A., Omari, K. E., Duman, R., Wagner, A., & Mancini, E. (2021). Phosphorus and sulfur SAD phasing of the nucleic acid-bound DNA-binding domain of interferon regulatory factor 4. Acta Crystallographica Section F: Structural Biology Communications, 77(7), 202-207. doi:10.1107/S2053230X21006506
  Article. View on figshare.
• Wagstaff, M., Tsaponina, O., Caalim, G., Greenfield, H., Milton-Harris, L., Mancini, E. J., . . . Morgan, R. G. (2021). Crosstalk between β-catenin and WT1 signalling activity in acute myeloid leukemia. doi:10.1101/2021.11.06.467095
  Article. View online.

2020

• Piepoli, S., Alt, A. O., Atilgan, C., Mancini, E., & Erman, B. (2020). Structural analysis of the PATZ1 BTB domain homodimer. Acta Crystallographica Section D: Structural Biology, 76, 581-593. doi:10.1107/S2059798320005355
  Article. View on figshare.
• Milton-Harris, L., Jeeves, M., Walker, S. A., Ward, S. E., & Mancini, E. (2020). Small molecule inhibits T-cell acute lymphoblastic leukaemia oncogenic interaction through conformational modulation of LMO2. Oncotarget, 11, 1737-1748. doi:10.18632/oncotarget.27580
  Article. View on figshare.
• Karia, D., Gilbert, R. C. G., Biasutto, A. J., Porcher, C., & Mancini, E. (n.d.). The histone H3K4 demethylase JARID1A directly interacts with haematopoietic transcription factor GATA1 in erythroid cells through its second PHD domain. Royal Society Open Science, 7(1), pages. doi:10.1098/rsos.191048
  Article. View on figshare.
• Piepoli, S., Alt, A. O., Atilgan, C., Mancini, E., & Erman, B. (2020). Structural Analysis of the PATZ1 BTB domain homodimer. doi:10.1101/2020.01.13.903898
  Article. View online.

2019

• Biasutto, A. J., West, P. M., Mancini, E. J., & Redfield, C. (2019). ¹H, ¹³C and ¹⁵N resonance assignments for the tandem CUE domains from chromatin remodeler SMARCAD1. Biomolecular NMR Assignments, 13(2), 261-265. doi:10.1007/s12104-019-09888-9
  Article. View online.
• Ponnusamy, R., Khatri, R., Correia, P. B., Wood, C. D., Mancini, E. J., Farrell, P. J., & West, M. J. (2019). Increased association between Epstein-Barr virus EBNA2 from type 2 strains and the transcriptional repressor BS69 restricts EBNA2 activity. PLoS Pathogens, 15(7). doi:10.1371/journal.ppat.1007458
  Article. View online.

2018

• Ponnusamy, R., Khatri, R., Correia, P., Mancini, E., Farrell, P., & West, M. (2018). Increased association between Epstein-Barr virus EBNA2 from type 2 strains and the transcriptional repressor BS69 restricts B cell growth. doi:10.1101/464131
  Article. View online.
• Agnarelli, A., Chevassut, T., & Mancini, E. (2018). IRF4 in multiple myeloma—biology, disease and therapeutic target. Leukemia Research, 72, 52-58. doi:10.1016/j.leukres.2018.07.025
  Article. View on figshare.
• Almohammed, R., Osborn, K., Ramasubramanyan, S., Perez-Fernandez, I. B. N., Godfrey, A., Mancini, E., & Sinclair, A. (2018). Mechanism of activation of the BNLF2a immune evasion gene of Epstein-Barr virus by Zta. Journal of General Virology, 99, 805-817. doi:10.1099/jgv.0.001056
  Article. View on figshare.

2016

• Wilson, R. H. C., Biasutto, A. J., Wang, L., Fischer, R., Baple, E. L., Crosby, A. H., . . . Green, C. M. (2016). PCNA dependent cellular activities tolerate dramatic perturbations in PCNA client interactions. DNA Repair, 50, 22-35. doi:10.1016/j.dnarep.2016.12.003
  Article. View on figshare.
• Morra, R., Fessl, T., Wang, Y., Mancini, E. J., & Tuma, R. (2016). Biophysical characterization of chromatin remodeling protein CHD4. Unknown Journal, 1431, 175-193. doi:10.1007/978-1-4939-3631-1_14
  Article. View online.

2015

• Mancini, E., & West, M. (n.d.). How to be a pioneer: a one-sided view. Trends in Biochemical Sciences, 40(10), 547-548. doi:10.1016/j.tibs.2015.08.011
  Article. View on figshare.
• Vivante, A., Kleppa, M. -J., Schulz, J., Kohl, S., Sharma, A., Chen, J., . . . Hildebrandt, F. (2015). Mutations in TBX18 cause dominant urinary tract malformations via transcriptional dysregulation of ureter development. American Journal of Human Genetics, 97(2), 291-301. doi:10.1016/j.ajhg.2015.07.001
  Article. View on figshare.

2014

• Walport, L. J., Morra, R., Mancini, E., & Redfield, C. (2015). 1H, 13C, and 15N resonance assignments for the tandem PHD finger motifs of human CHD4. Biomolecular NMR Assignments, 9(2), 239-242. doi:10.1007/s12104-014-9582-y
  Article. View on figshare.
• Sewell, H., Tanaka, T., Omari, K. E., Mancini, E., Cruz, A., Fernandez-Fuentes, N., . . . Rabbitts, T. H. (2015). Conformational flexibility of the oncogenic protein LMO2 primes the formation of the multi-protein transcription complex. Scientific Reports, 4(1), pages. doi:10.1038/srep03643
  Article. View on figshare.

2013

• Omari, K. E., Sutton, G., Ravantti, J. J., Zhang, H., Walter, T. S., Grimes, J. M., . . . Mancini, E. (2013). Plate tectonics of virus shell assembly and reorganization in phage f8, a distant relative of mammalian reoviruses. Structure, 21(8), 1384-1395. doi:10.1016/j.str.2013.06.017
  Article. View on figshare.
• Omari, K. E., Hoosdally, S. J., Tuladhar, K., Karia, D., Hall-Ponselé, E., Platonova, O., . . . Mancini, E. (2013). Structural basis for LMO2-driven recruitment of the SCL: E47bHLH heterodimer to hematopoietic-specific transcriptional targets. Cell Reports, 4(1), 135-147. doi:10.1016/j.celrep.2013.06.008
  Article. View on figshare.
• Omari, K. E., Meier, C., Kainov, D., Sutton, G., Grimes, J. M., Poranen, M. M., . . . Mancini, E. (2013). Tracking in atomic detail the functional specializations in viral RecA helicases that occur during evolution. Nucleic Acids Research, 41(20), 9396-9410. doi:10.1093/nar/gkt713
  Article. View on figshare.

2012

• Morra, R., Lee, B. M., Shaw, H., Tuma, R., & Mancini, E. (2012). Concerted action of the PHD, chromo and motor domains regulates the human chromatin remodelling ATPase CHD4. FEBS Letters, 586(16), 2513-2521. doi:10.1016/j.febslet.2012.06.017
  Article. View on figshare.
• Omari, K. E., De Mesmaeker, J., Karia, D., Ginn, H., Bhattacharya, S., & Mancini, E. (2012). Structure of the DNA-bound T-box domain of human TBX1, a transcription factor associated with the DiGeorge syndrome. Proteins, 80(2), 655-660. doi:10.1002/prot.23208
  Article. View on figshare.
• Mancini, E., & Tuma, R. (2012). Mechanism of RNA packaging motor. Advances in Experimental Medicine and Biology, 726, 609-629. doi:10.1007/978-1-4614-0980-9_27
  Article. View on figshare.

2011

• Omari, K. E., Hoosdally, S. J., Tuladhar, K., Karia, D., Vyas, P., Patient, R., . . . Mancini, E. (2011). Structure of the leukemia oncogene LMO2: implications for the assembly of a hematopoietic transcription factor complex. Blood, 117(7), 2146-2156. doi:10.1182/blood-2010-07-293357
  Article. View on figshare.

2010

• Omari, K. E., Porcher, C., & Mancini, E. (2010). Purification, crystallization and preliminary X-ray analysis of a fusion of the LIM domains of LMO2 and the LID domain of Ldb1. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 66(11), 1466-1469. doi:10.1107/S1744309110032872
  Article. View on figshare.
• Bollati, M., Alvarez, K., Assenberg, R., Baronti, C., Canard, B., Cook, S., . . . Bolognesi, M. (2010). Structure and functionality in flavivirus NS-proteins: perspectives for drug design. Antiviral Research, 87(2), 125-148. doi:10.1016/j.antiviral.2009.11.009
  Article. View on figshare.

2009

• Assenberg, R., Mastrangelo, E., Walter, T. S., Verma, A., Milani, M., Owens, R. J., . . . Mancini, E. (2009). Crystal structure of a novel conformational state of the flavivirus NS3 protein: Implications for polyprotein processing and viral replication. Journal of Virology, 83(24), 12895-12906. doi:10.1128/JVI.00942-09
  Article. View on figshare.

2008

• Meier, C., Carter, L. G., Sainsbury, S., Mancini, E., Owens, R. J., Stuart, D. I., & Esnouf, R. M. (2008). The crystal structure of UMP Kinase from Bacillus anthracis (BA1797) reveals an allosteric nucleotide-binding site. Journal of Molecular Biology, 381(5), 1098-1105. doi:10.1016/j.jmb.2008.06.078
  Article. View on figshare.
• Telenius, J., Wallin, A. E., Straka, M., Zhang, H., Mancini, E., & Tuma, R. (2008). RNA packaging motor: From structure to quantum mechanical modelling and sequential-stochastic mechanism. Computational and Mathematical Methods in Medicine, 9(3-4), 351-369. doi:10.1080/17486700802168502
  Article. View on figshare.
• Martin, M. C., Allan, L. A., Mancini, E., & Clarke, P. R. (2008). The docking interaction of caspase-9 with ERK2 provides a mechanism for the selective inhibitory phosphorylation of caspase-9 at threonine 125. Journal of Biological Chemistry, 283(7), 3854-3865. doi:10.1074/jbc.M705647200
  Article. View on figshare.
• Kainov, D. E., Mancini, E., Telenius, J., Lísal, J., Grimes, J. M., Bamford, D. H., . . . Tuma, R. (2008). Structural basis of mechanochemical coupling in a hexameric molecular motor. Journal of Biological Chemistry, 283(6), 3607-3617. doi:10.1074/jbc.M706366200
  Article. View on figshare.
• Walter, T. S., Mancini, E., Kadlec, J., Graham, S. C., Assenberg, R., Ren, J., . . . Harlos, K. (2008). Semi-automated microseeding of nanolitre crystallization experiments. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 64(1), 14-18. doi:10.1107/S1744309107057260
  Article. View on figshare.

2007

• Mancini, E., Assenberg, R., Verma, A., Walter, T. S., Tuma, R., Grimes, J. M., . . . Stuart, D. I. (2007). Structure of the Murray Valley encephalitis virus RNA helicase at 1.9 Å resolution. Protein Science, 16(10), 2294-2300. doi:10.1110/ps.072843107
  Article. View on figshare.

2006

• Kainov, D. E., Tuma, R., & Mancini, E. (2006). Hexameric molecular motors: P4 packaging ATPase unravels the mechanism. Cellular and Molecular Life Sciences, 63(10), 1095-1105. doi:10.1007/s00018-005-5450-3
  Article. View on figshare.

2005

• Meier, C., Mancini, E., Bamford, D. H., Walsh, M. A., Stuart, D. I., & Grimes, J. M. (2005). Overcoming the false-minima problem in direct methods: Structure determination of the packaging enzyme P4 from bacteriophage f13. Acta Crystallographica Section D: Biological Crystallography, 61(9), 1238-1244. doi:10.1107/S0907444905019761
  Article. View on figshare.

2004

• Mancini, E., Kainov, D. E., Grimes, J. M., Tuma, R., Bamford, D. H., & Stuart, D. I. (2004). Atomic snapshots of an RNA packaging motor reveal conformational changes linking ATP hydrolysis to RNA translocation. Cell, 118(6), 743-755. doi:10.1016/j.cell.2004.09.007
  Article. View on figshare.
• Mancini, E., Kainov, D. E., Wei, H., Gottlieb, P., Tuma, R., Bamford, D. H., . . . Grimes, J. M. (2004). Production, crystallization and preliminary X-ray crystallographic studies of the bacteriophage f12 packaging motor. Acta Crystallographica Section D: Biological Crystallography, 60(3), 588-590. doi:10.1107/S0907444904001052
  Article. View on figshare.

2003

• Mancini, E., Grimes, J. M., Malby, R., Sutton, G. C., Kainov, D. E., Juuti, J. T., . . . Stuart, D. I. (2003). Order and disorder in crystals of hexameric NTPases from dsRNA bacteriophages. Acta Crystallographica Section D: Biological Crystallography, 59(12), 2337-2341. doi:10.1107/S0907444903018729
  Article. View on figshare.
• Brown, J., Walter, T. S., Carter, L., Abrescia, N. G. A., Aricescu, A. R., Batuwangala, T. D., . . . Stuart, D. I. (2003). A procedure for setting up high-throughput nanolitre crystallization experiments. II. Crystallization results. Journal of Applied Crystallography, 36(2), 315-318. doi:10.1107/S0021889803002012
  Article. View on figshare.
• Mancini, E. J. (2003). Structural biology of viruses: A case of synergy. In HIGHLIGHTS IN CONDENSED MATTER PHYSICS Vol. 695 (pp. 333-338). Retrieved from https://www.webofscience.com/
  Conference publication.

2002

• Fuller, S., Gowen, B., Brady, S., Watson, B., Briggs, J., Mancini, E., & Matadeen, R. (2002). Cryo-electron microscopy of large complexes: a cold look at fusion. Microscopy and Microanalysis, 8(S02), 1016-1017.
  Article. View on figshare.
• Fuller, S., Gowen, B., Brady, S., Watson, B., Briggs, J., Mancini, E., & Matadeen, R. (2002). Cryo-electron microscopy of large complexes: A cold look at fusion. Microscopy and Microanalysis, 8(SUPPL. 2), 1016-1017. doi:10.1017/s1431927602102327
  Article. View online.

2000

• Mancini, E., & Fuller, S. D. (2000). Supplanting crystallography or supplementing microscopy? A combined approach to the study of an enveloped virus. Acta Crystallographica Section D: Biological Crystallography, 56(10), 1278-1287. doi:10.1107/S0907444900010817
  Article. View on figshare.
• Mancini, E., Clarke, M., Gowen, B. E., Rutten, T., & Fuller, S. D. (2000). Cryo-electron microscopy reveals the functional organization of an enveloped virus, Semliki Forest virus. Molecular Cell, 5(2), 255-266. doi:10.1016/S1097-2765(00)80421-9
  Article. View on figshare.

1998

• Ferlenghi, I., Gowen, B., de Haas, F., Mancini, E., Garoff, H., Sjöberg, M., & Fuller, S. D. (1998). The first step: activation of the semliki forest virus spike protein precursor causes a localized conformational change in the trimeric spike. Journal of Molecular Biology, 283(1), 71-81. doi:10.1006/jmbi.1998.2066
  Article. View on figshare.

1997

• Mancini, E., de Haas, F., & Fuller, S. D. (1997). High-resolution icosahedral reconstruction: fulfilling the promise of cryo-electron microscopy. Structure, 5(6), 741-750. doi:10.1016/S0969-2126(97)00229-3
  Article. View on figshare.
• Amendolia, S. R., Beccherle, R., Bertolucci, E., Bisogni, M. G., Bottigli, U., Campbell, M., . . . Stefanini, A. (1997). Use of silicon and GaAs pixel detectors for digital autoradiography. In IEEE TRANSACTIONS ON NUCLEAR SCIENCE Vol. 44 (pp. 929-933). doi:10.1109/23.603779
  Conference publication. View online.
• DaVia, C., Bates, R., Bertolucci, E., Bottigli, U., Campbell, M., Chesi, E., . . . Stefanini, A. (1997). Gallium arsenide pixel detectors for medical imaging. In NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT Vol. 395 (pp. 148-151). doi:10.1016/S0168-9002(97)00631-1
  Conference publication. View online.
• Bertolucci, E., Conti, M., Grossi, G., Mancini, E., Russo, P., Campbell, M., . . . Stefanini, A. (1997). Use of silicon and GaAs pixel detectors for digital autoradiography. In 1996 IEEE NUCLEAR SCIENCE SYMPOSIUM - CONFERENCE RECORD, VOLS 1-3 (pp. 835-839). Retrieved from https://www.webofscience.com/
  Conference publication.

1996

• Bertolucci, E., Conti, M., Grossi, G., Madonna, G., Mancini, E., Russo, P., . . . Amendolia, S. R. (1996). Autoradiography with silicon strip detectors. NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 381(2-3), 527-530. doi:10.1016/S0168-9002(96)00736-X
  Article. View online.