Life Sciences

Synaptic Communication

Module code: C1120
Level 6
15 credits in autumn semester
Teaching method: Lecture
Assessment modes: Coursework, Computer based exam

This module explores aspects of neuronal signalling, in both vertebrates and invertebrates, highlighting how molecular structure relates to function in signalling pathways. The emphasis will be on understanding how molecular and cellular mechanisms underlie the function of the CNS at a systems level and the generation of behaviour.

The module begins with the problem of sensory transduction (getting information into the nervous system), with a particular emphasis on mechanical (auditory) and visual modalities. This will be followed by a series of lectures on how information is processed at the synapse, covering electrical transmission and preand post-synaptic mechanisms at the chemical synapse. You will also be introduced to non-synaptic information processing.

Module learning outcomes

• Demonstrate an understanding of the role of molecular and macromolecular structures in pre- and post-synaptic function and the in vitro and in vivo experimental approaches that are used to investigate synaptic mechanisms.
• Demonstrate a knowledge and systematic understanding of key molecular mechanisms involved in sensory transduction
• Understand mechanisms contributing to synaptic plasticity and its role in learning and memory
• Demonstrate an understanding of the scientific process and how to design and evaluate appropriate experiments for testing a hypothesis