Life Sciences

Genomics and Bioinformatics

Module code: C7120
Level 6
15 credits in spring semester
Teaching method: Seminar, Lecture, Practical, Class
Assessment modes: Coursework, Computer based exam

This module will introduce the common types of genomic and proteomic data available in biological databases; including DNA and protein sequences, motifs, gene structure, protein interactions and expression profiles. The aims and methods of DNA and protein sequence analysis will be covered, including analysis of homology, identification of motifs and domains, pair-wise and multiple alignments and prediction of gene structure.

The practical sessions will include the analysis of DNA and protein sequence data from biological databases. In these sessions you will learn how to integrate data to find the functional links between disease related genes and proteins.

Module learning outcomes

• Show a systematic understanding of the types of biological data stored in public databases and how these data are organised and accessed
• A systematic understanding and the ability to deploy methods for the analysis of sequence homology and function
• Critically evaluate bioinformatics data to demonstrate how links can be made between genes and proteins involved in disease processes
• Access, manipulate and analyse biological data from public databases using web-based tools to initiate and carry out independent projects