Life Sciences

Structural Basis of Biological Function

Module code: C7114
Level 5
15 credits in autumn semester
Teaching method: Laboratory, Post lab, Pre lab, Workshop, Lecture, Seminar
Assessment modes: Coursework, Computer based exam

Explore how the structures of protein molecules have evolved to deliver the central functions of life. 

The module consists of lectures supported by a workshop, a seminar and a lab practical. You’ll be introduced to the diverse nature of proteins, the principles of protein architecture and the evolution of protein families. In addition you’ll cover:

• molecular motors
• membrane proteins
• post-translational modifications
• protein folding
• protein interactions with DNA.

You’ll develop employability skills through assessing and interpreting data, using appropriate statistical methods and graphical tools.

Module learning outcomes

• Explain, in detail, the principles of protein architecture and the evolution of protein families
• Describe the role of protein structure in controlling protein function
• Describe the mechanism of protein folding, the role of post-translational modifications and the structure of molecular chaperones and motors.
• Utilise knowledge of the acquisition of relevant quantitative laboratory results to assess and interpret data using appropriate statistical methods and graphical tools.