Thomas Stiff
School Associate (Life Sciences)

Selected publications

Article

Stiff, Tom, Casar Tena, Teresa, O'Driscoll, Mark, Jeggo, Penny A and Philipp, Melanie (2016) ATR promotes cilia signalling: links to developmental impacts. Human molecular genetics, 25 (8). pp. 1574-1587. ISSN 1460-2083

Stiff, Tom, Casar Tena, Teresa, O'Driscoll, Mark, Jeggo, Penny A and Philipp, Melanie (2016) ATR promotes cilia signalling: links to developmental impacts. Human Molecular Genetics, 25 (8). pp. 1574-1587. ISSN 0964-6906

Stiff, Tom, Alagoz, Meryem, Alcantara, Diana, Outwin, Emily, Brunner, Han G, Bongers, Ernie M H F, O'Driscoll, Mark and Jeggo, Penny A (2013) Deficiency in origin licensing proteins impairs cilia formation: implications for the aetiology of meier-gorlin syndrome. PLoS Genetics, 9 (3). e1003360. ISSN 1553-7404

Murray, Johanne M, Stiff, Tom and Jeggo, Penny A (2012) DNA double-strand break repair within heterochromatic regions. Biochemical Society Transactions, 40 (1). pp. 173-178. ISSN 0300-5127

Ogi, Tomoo, Walker, Sarah, Stiff, Tom, Hobson, Emma, Limsirichaikul, Siripan, Carpenter, Gillian, Prescott, Katrina, Suri, Mohnish, Byrd, Philip J, Matsuse, Michiko, Mitsutake, Norisato, Nakazawa, Yuka, Vasudevan, Pradeep, Barrow, Margaret, Stewart, Grant S, Taylor, A Malcolm R, O'Driscoll, Mark and Jeggo, Penny A (2012) Identification of the first ATRIP-deficient patient and novel mutations in ATR define a clinical spectrum for ATR-ATRIP Seckel Syndrome. PLoS Genetics, 8 (11). e1002945. ISSN 1553-7390

Deckbar, Dorothee, Stiff, Thomas, Kock, Barbara, Reis, Caroline, Löbrich, Markus and Jeggo, Penny (2010) The limitations of the G1-S checkpoint. Cancer Research, 70 (11). pp. 4412-4421. ISSN 0008-5472

Riballo, Enriqueta, Woodbine, Lisa, Stiff, Thomas, Walker, Sarah A., Goodarzi, Aaron A. and Jeggo, Penny A. (2009) XLF-Cernunnos promotes DNA ligase IV-XRCC4 re-adenylation following ligation. Nucleic Acids Research, 37 (2). pp. 482-492. ISSN 0305-1048

Griffith, Elen, Walker, Sarah, Martin, Carol-Anne, Vagnarelli, Paola, Stiff, Tom, Vernay, Bertrand, Al Sanna, Nouriya, Saggar, Anand, Hamel, Ben, Earnshaw, William C, Jeggo, Penny A, Jackson, Andrew P and O'Driscoll, Mark (2007) Mutations in pericentrin cause Seckel syndrome with defective ATR-dependent DNA damage signaling. Nature Genetics, 40 (2). pp. 232-236. ISSN 1061-4036

Deckbar, Dorothee, Birraux, Julie, Krempler, Andrea, Tchouandong, Leopoldine, Beucher, Andrea, Walker, Sarah, Stiff, Tom, Jeggo, Penny and Löbrich, Markus (2007) Chromosome breakage after G2 checkpoint release. Journal of Cell Biology, 176 (6). pp. 749-755. ISSN 0021-9525

Stiff, Thomas, Walker, Sarah A, Cerosaletti, Karen, Goodarzi, Aaron A, Petermann, Eve, Concannon, Pat, O'Driscoll, Mark and Jeggo, Penny A (2006) ATR-dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling. EMBO Journal, 25 (24). pp. 5775-5782. ISSN 0261-4189

Stiff, Thomas, O'Driscoll, Mark, Rief, N, Iwabuchi, K, Lobrich, M and Jeggo, Penny (2004) ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation. Cancer Research, 64 (7). pp. 2390-2396. ISSN 00085472

Stiff, Thomas, O'Driscoll, Mark, Rief, N., Iwabuchi, K., Lobrich, M. and Jeggo, Penny (2004) ATM and DNA-PK function redundantly to phosphorylate H2AX following exposure to ioninsing radiation. Cancer Research, 64 (7). pp. 2390-2396. ISSN 0008-5472

Stiff, Thomas, Shtivelman, E, Jeggo, Penny and Kysela, B (2004) AHNAK interacts with the DNA ligase IV-XRCC4 complex and stimulates DNA ligase IV-mediated double-stranded ligation. DNA Repair, 3 (3). pp. 245-256. ISSN 15687864

Stiff, Thomas, Shtivelman, E., Jeggo, Penny and Kysela, B. (2004) AHNAK interacts with the DNA ligase IV-XRCC4 complex and stimulates DNA ligase IV mediated double stranded ligation. DNA Repair, 3. pp. 245-256. ISSN 1568-7864