Research at Sussex comprises all aspects of the regulation of gene expression studying how the flow of information from DNA to protein is controlled. This includes the investigation of gene structure, transcriptional regulation and chromatin remodelling, mRNA splicing, polyadenylation, localisation, degradation and stability, microRNA regulation and translational control. The impact and role of these control steps is studied in many key contexts including animal development, tissue differentiation and function, cell growth, carcinogenesis and antibiotic and biofuel production.