Professor Corne Kros
Article
Prayuenyong, Pattarawadee, Baguley, David M, Kros, Corné J and Steyger, Peter (2021) Preferential Cochleotoxicity of Cisplatin. Frontiers in Neuroscience, 15. a695268 1-8. ISSN 1662-4548
Kenyon, Emma J, Kirkwood, Nerissa K, Kitcher, Sian R, Goodyear, Richard J, Derudas, Marco, Cantillon, Daire, Baxendale, Sarah, de la Vega de León, Antonio, Mahieu, Virginia N, Osgood, Richard T, Wilson, Charlotte Donald, Bull, James C, Waddell, Simon J, Whitfield, Tanya T, Ward, Simon E, Kros, Corne J and Richardson, Guy P (2021) Identification of a series of hair-cell MET channel blockers that protect against aminoglycoside-induced ototoxicity. JCI Insight, 6 (7). a145704 1-22. ISSN 2379-3708
Jeng, Jing -Yi, Ceriani, Federico, Hendry, Aenea, Johnson, Stuart L, Yen, Piece, Simmons, Dwayne D, Kros, Corne J and Marcotti, Walter (2020) Hair cell maturation is differentially regulated along the tonotopic axis of the mammalian cochlea. Journal of Physiology, 598 (1). pp. 151-170. ISSN 0022-3751
O’Reilly, Molly, Young, Luke, Kirkwood, Nerissa K, Richardson, Guy P, Kros, Corné J and Moore, Anthony L (2019) Gentamicin affects the bioenergetics of isolated mitochondria and collapses the mitochondrial membrane potential in cochlear sensory hair cells. Frontiers in Cellular Neuroscience, 13 (a416). pp. 1-12. ISSN 1662-5102
Kitcher, Siân R, Kirkwood, Nerissa K, Camci, Esra D, Wu, Patricia, Gibson, Robin M, Redila, Van A, Ogelman, Roberto, Simon, Julian A, Rubel, Edwin W, Raible, David W, Richardson, Guy P and Kros, Corné J (2019) ORC-13661 protects sensory hair cells from aminoglycoside and cisplatin ototoxicity. JCI Insight, 4 (15). pp. 1-19. ISSN 2379-3708
O'Reilly, Molly, Kirkwood, Nerissa K, Kenyon, Emma J, Huckvale, Rosemary, Cantillon, Daire M, Waddell, Simon J, Ward, Simon E, Richardson, Guy P, Kros, Corné J and Derudas, Marco (2019) Design, synthesis and biological evaluation of a new series of carvedilol derivatives that protect sensory hair cells from aminoglycoside-induced damage by blocking the mechanoelectrical transducer channel. Journal of Medicinal Chemistry, 62 (11). pp. 5312-5329. ISSN 0022-2623
Ceriani, Federico, Hendry, Aenea, Jeng, Jing‐Yi, Johnson, Stuart L, Stephani, Friederike, Olt, Jennifer, Holley, Matthew C, Mammano, Fabio, Engel, Jutta, Kros, Corné J, Simmons, Dwayne D and Marcotti, Walter (2019) Coordinated calcium signalling in cochlear sensory and non‐sensory cells refines afferent innervation of outer hair cells. EMBO Journal, 38 (9). e99839 1-19. ISSN 1460-2075
Corns, Laura F, Johnson, Stuart L, Roberts, Terri, Ranatunga, Kishani M, Hendry, Aenea, Ceriani, Federico, Safieddine, Saaid, Steel, Karen P, Forge, Andy, Petit, Christine, Furness, David N, Kros, Corné J and Marcotti, Walter (2018) Mechanotransduction is required for establishing and maintaining mature inner hair cells and regulating efferent innervation. Nature Communications, 9 (4015). pp. 1-15. ISSN 2041-1723
Jeong, Minjin, O'Reilly, Molly, Kirkwood, Nerissa K, Al-Aama, Jumana, Lako, Majlinda, Kros, Corné J and Armstrong, Lyle (2018) Generating inner ear organoids containing putative cochlear hair cells from human pluripotent stem cells. Cell Death & Disease, 9 (9922). pp. 1-13. ISSN 2041-4889
Kenyon, Emma J, Kirkwood, Nerissa K, Kitcher, Siân R, O'Reilly, Molly, Derudas, Marco, Cantillon, Daire M, Goodyear, Richard J, Secker, Abigail, Baxendale, Sarah, Bulley, James C, Waddell, Simon J, Whitfield, Tanya T, Ward, Simon E, Kros, Corné J and Richardson, Guy P (2017) Identification of ion-channel modulators that protect against aminoglycoside-induced hair cell death. Journal of Clinical Investigation Insight, 2 (24). a96773 1-16. ISSN 2379-3708
Corns, Laura F, Jeng, Jing-Yi, Richardson, Guy P, Kros, Corné J and Marcotti, Walter (2017) TMC2 modifies permeation properties of the mechanoelectrical transducer channel in early postnatal mouse cochlear outer hair cells. Frontiers in Molecular Neuroscience, 10. ISSN 1662-5099
Kirkwood, Nerissa K, O'Reilly, Molly, Derudas, Marco, Kenyon, Emma J, Huckvale, Rosemary, van Netten, Sietse M, Ward, Simon E, Richardson, Guy P and Kros, Corné Kros (2017) d-Tubocurarine and berbamine: alkaloids that are permeant blockers of the hair cell's mechano-electrical transducer channel and protect from aminoglycoside toxicity. Frontiers in Cellular Neuroscience, 11. ISSN 1662-5102
Marcotti, Walter, Corns, Laura F, Goodyear, Richard J, Rzadzinska, Agnieszka K, Avraham, Karen B, Steel, Karen P, Richardson, Guy P and Kros, Corné J (2016) The acquisition of mechano-electrical transducer current adaptation in auditory hair cells requires myosin VI. Journal of Physiology, 594 (13). pp. 3667-3681. ISSN 0022-3751
Corns, Laura F, Johnson, Stuart L, Kros, Corne J and Marcotti, Walter (2016) Tmc1 point mutation affects Ca2+ sensitivity and block by dihydrostreptomycin of the mechanoelectrical transducer current of mouse outer hair cells. Journal of Neuroscience, 36 (2). pp. 336-349. ISSN 0270-6474
Sexton, Jane E, Desmonds, Terri, Quick, Kathryn, Taylor, Ruth, Abramowitz, Joel, Forge, Andy, Kros, Corné J, Birnbaumer, Lutz and Wood, John N (2016) The contribution of TRPC1, TRPC3, TRPC5 and TRPC6 to touch and hearing. Neuroscience Letters, 610. pp. 36-42. ISSN 0304-3940
Corns, Laura F, Johnson, Stuart L, Kros, Corné J and Marcotti, Walter (2014) Calcium entry into stereocilia drives adaptation of the mechanoelectrical transducer current of mammalian cochlear hair cells. Proceedings of the National Academy of Sciences, 111 (41). pp. 14918-14923. ISSN 1091-6490
Marcotti, Walter, Corns, Laura F, Desmonds, Terri, Kirkwood, Nerissa K, Richardson, Guy P and Kros, Corné J (2014) Transduction without tip links in cochlear hair cells is mediated by ion channels with permeation properties distinct from those of the mechano-electrical transducer channel. Journal of Neuroscience, 34 (16). pp. 5505-5514. ISSN 0270-6474
Michalski, Nicolas, Michel, Vincent, Caberlotto, Elisa, Lefèvre, Gaelle M, Van Aken, Alexander F J, Tinevez, Jean-Yves, Bizard, Emilie, Houbron, Christophe, Weil, Dominique, Hardelin, Jean-Pierre, Richardson, Guy P, Kros, Corné J, Martin, Pascal and Petit, Christine (2009) Harmonin-b, an actin-binding scaffold protein, is involved in the adaptation of mechanoelectrical transduction by sensory hair cells. Pflügers Archiv European Journal of Physiology, 459 (1). pp. 115-130. ISSN 0031-6768
Van Aken, Alexander F J, Atiba-Davies, Margaret, Marcotti, Walter, Goodyear, Richard J, Bryant, Jane E, Richardson, Guy P, Noben-Trauth, Konrad and Kros, Corné J (2008) TRPML3 mutations cause impaired mechano-electrical transduction and depolarization by an inward-rectifier cation current in auditory hair cells of varitint-waddler mice. Journal of Physiology, 586 (22). pp. 5403-5418. ISSN 0022-3751