Important recent papers

Total synthesis of the thiopeptide promothiocin A, Bagley, M. C.; Bashford, K. E.; Hesketh, C. L.; Moody, C. J. J. Am. Chem. Soc. 2000, 122, 3301–3313;

One-pot multistep Bohlmann-Rahtz heteroannulation reactions: synthesis of dimethyl sulfomycinamate, Bagley, M. C.; Chapaneri, K.; Dale, J. W.; Xiong, X.; Bower, J. J. Org. Chem. 2005, 70, 1389–1399;

A simple continuous flow microwave reactor, Bagley, M. C.; Jenkins, R. L.; Lubinu, M. C.; Mason, C.; Wood, R. J. Org. Chem. 2005, 70, 7003–7006;

Microwave-assisted synthesis of N-pyrazole ureas and the p38 inhibitor BIRB 796 for study into accelerated cell ageing, Bagley, M. C.; Davis, T.; Dix, M. C.; Widdowson, C. S.; Kipling, D. Org. Biomol. Chem. 2006, 4, 4158–4164;

Rapid synthesis of 3-cyanopyridine-derived chromophores with two-dimensional tunability and solvatochromic photophysical properties, Bagley, M. C.; Lin, Z.; Pope, S. J. A. Chem. Commun. 2009, 5165-5167;

Microwave–Assisted Ullmann–Type C–S Bond Formation in the Synthesis of the P38α MAPK Clinical Candidate VX–745, Bagley, M. C.; Davis, T.; Dix, M. C.; Fusillo, V.; Pigeaux, M.; Rokicki, M. J.; Kipling, D. J. Org. Chem. 2009, 74, 8336-8342;

Microwave-assisted synthesis of a pyrazolyl ketone library for evaluation as p38 MAPK inhibitors in Werner syndrome cells, Bagley, M. C.; Davis, T.; Dix, M. C.; Murziani, P. G. S.; Rokicki, M. J.; Kipling, D. Future Med. Chem. 2010, 2, 203-213;

Synthesis of the highly selective p38 MAPK inhibitor UR-13756 for possible therapeutic use in Werner syndrome, Bagley, M. C.; Davis, T.; Rokicki, M. J.; Widdowson, C. S.; Kipling, D. Future Med. Chem. 2010, 2, 193-201;

Use of p38 MAPK inhibitors for the treatment of Werner syndrome, Bagley, M. C.; Davis, T.; Murziani, P. G. S.; Widdowson, C. S.; Kipling, D. Pharmaceuticals 2010, 3, 1842-1872;

In vitro activity of P38 MAPK inhibitor-loaded particles for the long term intra-articular treatment of osteoarthritis, Pradal, J.; Jordan, O.; Gabay, C.; Guerne, P. A.; Bagley, M. C.; Doelker, E.; Allémann, E.; Waldburger, J. M. Ann. Rheum. Dis. 2011, 70, A78-A79