August 2024 – Jess publishes her first PhD paper
By: Juliet OBrien
Last updated: Wednesday, 16 October 2024
Jess Daily’s first paper of her PhD has been published in the journal Cortex.
It is entitled: “The effect of apolipoprotein E genotype on spatial processing in humans: A meta-analysis and systematic review”.
It was co- authored by Flavia De Luca, Sam Berens, Andy Field, Jennifer Rusted and Chris Bird.
This paper reviewed a series of studies testing the impact of carrying a ε4 allele of the apolipoprotein E (APOE4) gene – a major risk factor for Alzheimer's disease, on spatial cognition. In the meta-analysis, the authors included 122 studies on healthy human participants where an APOE4-carrier group (heterozygous or homozygous) could be compared to a homozygous APOE3-carrier group. Daly and colleagues found that the APOE4 carriers scored significantly lower than APOE3 carriers only on tests of spatial long-term memory, while in other subdomains of spatial cognition (spatial construction, spatial working memory, spatial reasoning, navigation) there were no effects of genotype. To read the paper, see link below:
https://www.sciencedirect.com/science/article/abs/pii/S0010945224001424